Human Oral Microbiome Taxon Description
Slackia exigua
Human Oral Taxon ID (HOT):602Synonym:
Eubacterium exiguum
Status:
Named - Cultured
Type Strain:
More info at StrainInfo
Classification:
Domain:Bacteria
Phylum:Actinobacteria
Class:Coriobacteriia
Order:Coriobacteriales
Family:Coriobacteriaceae
Genus:Slackia
Species:exigua
NCBI Taxonomy ID:
16S rRNA Sequence:
AF101240  [Entrez Link]
PubMed Search:17  [PubMed Link]
16S rRNA Alignment: View Alignment         Download Alignment         NoteNucleotide Search:32  [Entrez Nucleotide Link]
Phylogeny: View 16S rRNA tree         View all Tree filesProtein Search:3811  [Entrez Protein Link]
Prevalence by Molecular Cloning:
Clones seen = 2 / 34879 = 0.00573%
Rank Abundance = Tied for 409
Genome Sequence
1 View Genome
 
Hierarchy Structure:    Hide or show the hierarchy structure
General Information:
N/A
Phenotypic Characteristics:
Gram positive non-spore forming, non-motile bacillus
Obligate anaerobe
Cellular morphology: 0.5 x 1.0 um, singly or in clumps
Colonial morphology: translucent colonies < 1 mm diameter after prolonged incubation o­n BHI-blood agar
No detectable metabolic end-products after growth in PYG
GAC content of DNA:60-64 mol%
Prevalence and Source:
Has been isolated by at least 3 groups of investigators
Found in most subjects with periodontitis by DNA hybridization (Wade, unpublished)
Disease Associations:
Adult periodontitis [5]
Necrotic pulps [10]
Dentoalveolar abscesses [1]
References:
PubMed database:
[1] Wade WG, Lewis MA, Cheeseman SL, Absi EG, Bishop PA. An unclassified Eubacterium taxon in acute dento-alveolar abscess. J Med Microbiol. 1994 Feb;40(2):115-7  [PubMed]
[2] Downes J, Munson MA, Spratt DA, Kononen E, Tarkka E, Jousimies-Somer H, Wade WG. Characterisation of Eubacterium-like strains isolated from oral infections. J Med Microbiol. 2001 Nov;50(11):947-51  [PubMed]
[3] Hashimura T, Sato M, Hoshino E. Detection of Slackia exigua, Mogibacterium timidum and Eubacterium saphenum from pulpal and periradicular samples using the Polymerase Chain Reaction (PCR) method. Int Endod J. 2001 Sep;34(6):463-70  [PubMed]
[4] Wade WG, Downes J, Dymock D, Hiom SJ, Weightman AJ, Dewhirst FE, Paster BJ, Tzellas N, Coleman B. The family Coriobacteriaceae: reclassification of Eubacterium exiguum (Poco et al. 1996) and Peptostreptococcus heliotrinreducens (Lanigan 1976) as Slackia exigua gen. nov., comb. nov. and Slackia hel Int J Syst Bacteriol. 1999 Apr;49 Pt 2:595-600  [PubMed]
[5] Moore WE, Holdeman LV, Cato EP, Smibert RM, Burmeister JA, Ranney RR. Bacteriology of moderate (chronic) periodontitis in mature adult humans. Infect Immun. 1983 Nov;42(2):510-5  [PubMed]
[6] Poco SE Jr, Nakazawa F, Ikeda T, Sato M, Sato T, Hoshino E. Eubacterium exiguum sp. nov., isolated from human oral lesions. Int J Syst Bacteriol. 1996 Oct;46(4):1120-4  [PubMed]
[7] Booth V, Downes J, Van den Berg J, Wade WG. Gram-positive anaerobic bacilli in human periodontal disease. J Periodontal Res. 2004 Aug;39(4):213-20  [PubMed]
[8] Nakazawa F, Hoshino E. DNA-DNA relatedness and phylogenetic positions of Slackia exigua, Slackia heliotrinireducens, Eggerthella lenta, and other related bacteria. Oral Microbiol Immunol. 2004 Oct;19(5):343-6  [PubMed]
[9] Uematsu H, Sato N, Djais A, Hoshino E. Degradation of arginine by Slackia exigua ATCC 700122 and Cryptobacterium curtum ATCC 700683. Oral Microbiol Immunol. 2006 Dec;21(6):381-4  [PubMed]
Non-PubMed database:
[10] Sato TE, Hoshino E, Uematsu H, Noda T. Predominant obligate anaerobes in necrotic pulps of human deciduous teeth. Microb Ecol Health Dis 1993 6:269  
   
Curator:  
Creation Info:   Latest Modification:  Jacques,  2009-07-27 14:31:18

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