Human Oral Microbiome Taxon Description
Streptococcus gordonii
Human Oral Taxon ID (HOT):622Synonym:
Status:
Named - Cultured
Type Strain:
ATCC 10558, NCTC7865
More info at StrainInfo
Classification:
Domain:Bacteria
Phylum:Firmicutes
Class:Bacilli
Order:Lactobacillales
Family:Streptococcaceae
Genus:Streptococcus
Species:gordonii
NCBI Taxonomy ID:
16S rRNA Sequence:
AF003931  [Entrez Link]
PubMed Search:729  [PubMed Link]
16S rRNA Alignment: View Alignment         Download Alignment         NoteNucleotide Search:956  [Entrez Nucleotide Link]
Phylogeny: View 16S rRNA tree         View all Tree filesProtein Search:6716  [Entrez Protein Link]
Prevalence by Molecular Cloning:
Clones seen = 478 / 34879 = 1.37%
Rank Abundance = 10
Genome Sequence
1 View Genome
 
Hierarchy Structure:    Hide or show the hierarchy structure
General Information:
Viridans type of streptococci has had taxonomic revisions.  Previously designated as strains of Streptococcus sanguis subsp. sanguis [1,4].  Suggested that strain NCTC 3165, a strain of Streptococcus mitis, be included [4]. 
Cultivability:
Alpha-hemolytic colonies (0.7- 1.2 mm diameter) o­n blood agar and extensive greening o­n chocolate agar.   
Phenotypic Characteristics:
Facultatively anaerobic, Gram positive cocci, approximately 1 um in diameter, that grow in short chains in broth cultures.   Carbohydrates are femented primarily to lactic acid and no gas. Catalase negative.  Cell wall contains glycerol teichoic acid and rhamnose. Peptidoglycan type is Lys-Ala1-3

S. gordonii is similar to S. sanguis (sanguinis) but can be differentiated based o­n the following; DNA homology, lower G+C content of the DNA (42  vs 46 mol%), ferments amygdalin, has alkaline phosphatase and B-glucosaminidase activities, lacks IgA1 protease activity, multilocus enzyme analysis [4].

3 biovars of S. gordonii differ biochemically and serologically, but all biovars possess the group H antigen [4]

 
Prevalence and Source:
Commonly found in the human oral cavity and throat.  Has been isolated from blood and heart valves of patients with bacterial endocarditis.  May be found occasionally in human feces
Disease Associations:
Generally associated with healthy oral microflora, but has been associated with intact enamel in children with primary caries surfaces [2].  May play a role in caries production [3].

Has also been associated with infective endocarditis and recurrent aphthous ulcerations
References:
PubMed database:
[1] Coykendall AL, Specht PA. DNA base sequence homologies among strains of Streptococcus sanguis. J Gen Microbiol. 1975 Nov;91(1):92-8  [PubMed]
[2] Becker MR, Paster BJ, Leys EJ, Moeschberger ML, Kenyon SG, Galvin JL, Boches SK, Dewhirst FE, Griffen AL. Molecular analysis of bacterial species associated with childhood caries. J Clin Microbiol. 2002 Mar;40(3):1001-9  [PubMed]
[3] Sansone C, Van Houte J, Joshipura K, Kent R, Margolis HC. The association of mutans streptococci and non-mutans streptococci capable of acidogenesis at a low pH with dental caries on enamel and root surfaces. J Dent Res. 1993 Feb;72(2):508-16  [PubMed]
Non-PubMed database:
[4] Kilian M, Mikkelsen L, Henrichsen J. Taxonomic study of viridans Streptococci: Description of Streptococcus gordonii sp. nov. and emended descriptions of S. sanguis (White and Niven 1946), S. oralis .... Int J Syst Bacteriol. 1989 Oct;39(4):471-84.  
   
Curator:  
Creation Info:   Latest Modification:  abby,  2009-09-08 15:45:18

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