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Taxonomy: V4.2   |  16S rRNA RefSeq: V16.03   |  Genomic RefSeq: V11.02   |  Viruses: V1.2

Download HOMD Data



Genomic Meta Information::Batch Downloads
TypeFormats
All Genomic Metadata Tab Delimited Text
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MS Excel Format
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GTDB (V) Taxonomy
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MS Excel Format
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NCBI Genome Annotations[FTP Site for download]
PROKKA Genome Annotations[FTP Site for download]
Genomic Trees:
Conserved Protein, Ribosomal Protein and 16S rRNA
[FTP Site for download]

Phylogenetics
TypeFormats
Go To Current    [RefSeq]    [Genome]   FTP Directory
Phylogenetic tree of HOMD 16S rRNA Reference Sequences svg newick
Phylogenetic tree of 16S rRNA gene sequences identified in HOMD genomes svg newick Sequence ID table
Phylogenomic tree based on conserved proteins identified from HOMD genomes svg newick Sequence ID table
Phylogenetic tree of ribosomal proteins identified from HOMD genomes svg newick Sequence ID table

Protein/Peptide
Study-IDStudy NameFormats
7Persistent Immune and Clotting Dysfunction Detected in Saliva and Blood Plasma after COVID-19 Download CSV File



Download HOMD 16S rRNA Gene Sequences
HOMD provides two different sets of 16S rRNA Gene Reference Sequence (RefSeq) for download and BLAST search:

  1. HOMD 16S rRNA RefSeq: This set contains sequences representing all currently named and unnamed oral taxa.
  2. HOMD 16S rRNA Extended RefSeq: This set contains additional16S rRNA reference gene sequences that are 
      distinctively different from existing taxa but have not yet been assigned with a taxon ID.
  
A phylogeny-based, high-resolution, habitat-specific training reference sequence set was constructed to achieve species/supraspecies-level taxonomic assignment to short- and long-read 16S rRNA gene-derived amplicon sequence variants (ASVs). The training set sequences, together with the pipeline scripts, are available for download. For detail description of the training set and the pipelines, please refer to our publication Escapa et al, 2020.

In addition, the entire collection of all cloned sequences (clonal collection) upon which the Refseq was derived from, is also provided for download on this page and on the HOMD FTP site.
[View Version History]
Date Version Name
HOMD 16S rRNA RefSeq *Right-click to download
or click to open
2025-08-07eHOMD 16S rRNA RefSeq Version 16.03
2025-07-10eHOMD 16S rRNA RefSeq Version 16.02
2025-04-25eHOMD 16S rRNA RefSeq Version 16.0
2023-04-10eHOMD 16S rRNA RefSeq Version 15.23 (Starts from position 28)
2023-04-10eHOMD 16S rRNA RefSeq Version 15.23 (Starts from position 9)
2021-02-09eHOMD 16S rRNA RefSeq Version 15.22 (Starts from position 28)
2021-02-09eHOMD 16S rRNA RefSeq Version 15.22 (Starts from position 9)
2017-11-16eHOMD 16S rRNA RefSeq Version 15.1 (Starts from position 28)
2017-11-16eHOMD 16S rRNA RefSeq Version 15.1 (Starts from position 9)
2017-01-03HOMD 16S rRNA RefSeq Version 14.51 (Starts from position 28)
2017-01-03HOMD 16S rRNA RefSeq Version 14.51 (Starts from position 9)
2016-03-29HOMD 16S rRNA RefSeq Version 14.5 (Starts from position 28)
2016-03-29HOMD 16S rRNA RefSeq Version 14.5 (Starts from position 9)
2013-05-08HOMD 16S rRNA RefSeq Version 13.2 (Starts at position 28)
2013-05-08HOMD 16S rRNA RefSeq Version 13.2 (Starts at position 9)
2013-03-25HOMD 16S rRNA RefSeq Version 13.0
2013-01-16HOMD 16S rRNA RefSeq Version 12.0
2012-02-16HOMD 16S rRNA RefSeq Version 11.0
2010-02-08HOMD 16S rRNA RefSeq Version 10.1
2009-02-03HOMD 16S rRNA RefSeq Version 10
HOMD 16S rRNA Extended RefSeq *
2010-02-19HOMD 16S rRNA RefSeq Extended Version 1.1
2009-02-25HOMD 16S rRNA RefSeq Extended Version 1
HOMD 16S rRNA Gene Sequence Clonal Collection
2010-02-07HOMD 16S rRNA Gene Sequence Clonal Collection Version 1
eHOMD 16S rRNA training sequence sets
2018-12-03eHOMD 16S rRNA full-length training set
2018-12-03eHOMD 16S rRNA V1V3 training set
Other training set related files [link to FTP site] [Link Out]
Other Download Formats (FASTA, MOTHUR, QIIME, ...)
2025-08-25eHOMD 16S rRNA RefSeq Version V16.03 Taxonomy File for MOTHUR
2025-08-25eHOMD 16S rRNA RefSeq Version V16.03 Taxonomy File for QIIME
2025-09-04eHOMD 16S rRNA RefSeq Version 16.03 Aligned FASTA
2025-07-10eHOMD 16S rRNA RefSeq Version V16.02 Taxonomy File for MOTHUR
2025-07-10eHOMD 16S rRNA RefSeq Version V16.02 Taxonomy File for QIIME
2025-03-10eHOMD 16S rRNA RefSeq Version V16.0 Taxonomy File for MOTHUR
2025-03-10eHOMD 16S rRNA RefSeq Version V16.0 Taxonomy File for QIIME
2021-02-09eHOMD 16S rRNA RefSeq Version 15.23 Aligned FASTA File
2021-02-09eHOMD 16S rRNA RefSeq Version 15.23 Taxonomy File for MOTHUR
2021-02-09eHOMD 16S rRNA RefSeq Version 15.23 Taxonomy File for QIIME
2021-02-09eHOMD 16S rRNA RefSeq Version 15.22 Aligned FASTA File
2021-02-09eHOMD 16S rRNA RefSeq Version 15.22 Taxonomy File for MOTHUR
2021-02-09eHOMD 16S rRNA RefSeq Version 15.22 Taxonomy File for QIIME
2017-11-16eHOMD 16S rRNA RefSeq Version 15.1 Aligned FASTA File
2017-11-16eHOMD 16S rRNA RefSeq Version 15.1 Taxonomy File for MOTHUR
2017-11-16eHOMD 16S rRNA RefSeq Version 15.1 Taxonomy File for QIIME
2017-01-03HOMD 16S rRNA RefSeq Version 14.51 Aligned FASTA File
2017-01-03HOMD 16S rRNA RefSeq Version 14.51 Taxonomy File for MOTHUR
2017-01-03HOMD 16S rRNA RefSeq Version 14.51 Taxonomy File for QIIME
2016-03-29HOMD 16S rRNA RefSeq Version 14.5 Aligned FASTA File
2016-03-29HOMD 16S rRNA RefSeq Version 14.5 Taxonomy File for MOTHUR
2016-03-29HOMD 16S rRNA RefSeq Version 14.5 Taxonomy File for QIIME
2013-05-08HOMD 16S rRNA RefSeq Version 13.2 Aligned FASTA File
2013-05-08HOMD 16S rRNA RefSeq Version 13.2 FASTA File in QIIME Format
2014-09-11HOMD 16S rRNA RefSeq Version 13.2 FASTA File for mothur
2014-09-11HOMD 16S rRNA RefSeq Version 13.2 Taxonomy File for mothur
* These sequences are corrected consensus sequences. Many have been corrected and extended based on alignment with other sequences for that taxon and Ns and indels removed. Therefore, for many sequences, there will be differences between the Reference Sequence and the GenBank sequence listed in the header information. We have not yet updated our own GenBank sequences, and can not update those from other depositors. We believe these are currently the best reference sequences available, and for the purposes of BLAST analysis, have the advantage of being of a uniform length.

HOMD Database Schema (updated 2022-06-01)
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