HOMD Banner
16S rRNA RefSeq: V15.23    Genomic RefSeq: V10.1
Back To Tax Table
Prevotella intermedia (HMT-643)
Taxon Description:
Formerly known as Bacteroides melaninogenicus subsp. intermedius and then Bacteroides intermedius. Phylogenetic analysis based on 16S rRNA sequence comparisons and biochemical characteristics warranted separate genus designation to the genus Prevotella i.e. Prevotella intermedia [1].

Disease Associations:
Although commonly detected in subgingival plaque P. intermedia has been associated with periodontal disease [2] aggressive periodontitis necrotizing ulcerative periondontis endodontic infections [4] and facial gangrene (noma) [5]. Has also been linked to coronary artery disease [3].

Prevalence and Source:
Primarily colonizes the gingival crevice but also found in head neck abdominal and lung infections. Has been isolated from blood.
no image available

Class: Bacteroidia
Order: Bacteroidales
Genus: Prevotella
Species:Prevotella intermedia
Status: Named - Cultured
Type/Reference Strain: ATCC 25611
[Check LPSN.dsmz.de]
[Check Global Catalogue of Microorganisms]
Former Names or Synonyms:
Bacteroides intermedius
Bacteroides melaninogenicus
Phylum: Bacteroidetes
Prevotella intermedius
16S rRNA Reference Sequences:    view in
RefSeq tree
RefSeq ID: 643_2907
RefSeq ID: 643_3106

Download latest 16S rRNA reference gene sequences.
Genotypic Description:
Phenotypic Characteristics: Obligately anaerobic Gram negative short rod (0.5 by 2 um). Moderately saccaharolytic fermenting glucose and other carbohydrates to mainly to succinate and acetate. Cell walls contain meso-diaminopimelic acid but not KDO or heptose.
Cultivability: Black pigmented colonies (0.5- 2.0 mm diameter) after anaerobic incubation for 2 days on hemin-containing agar media. Hemin is required for growth Vitamin K is stimulatory. Colonies fluoresce under shortwave UV.
(Anvi`o-server hosted on VAMPS)
Microbial Ecology
[Open Abundance/Prevalence Page for ]
NCBI Taxon ID: 28131 [Link to NCBI]
PubMed Searches:
[NCBI PubMed Link]
[NCBI (Entrez) Nucleotide Link]
[NCBI (Entrez) Protein Link]
Number of
Genome Sequences:
32 See List
Phylogenetic Trees:
View in genome tree
View in ribosome protein tree
View in 16S rRNA gene tree

[1] Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent RL Jr. Microbial complexes in subgingival plaque. J Clin Periodontol. 1998 Feb;25(2):134-44
[2] Gomes BP, Jacinto RC, Pinheiro ET, Sousa EL, Zaia AA, Ferraz CC, Souza-Filho FJ. Porphyromonas gingivalis, Porphyromonas endodontalis, Prevotella intermedia and Prevotella nigrescens in endodontic lesions detected by culture and by PCR. Oral Microbiol Immunol. 2005 Aug;20(4):211-5
[3] Enwonwu CO, Falkler WA, Idigbe EO. Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms. Crit Rev Oral Biol Med. 2000;11(2):159-71
[4] Nonnenmacher C, Stelzel M, Susin C, Sattler AM, Schaefer JR, Maisch B, Mutters R, Flores-de-Jacoby L. Periodontal microbiota in patients with coronary artery disease measured by real-time polymerase chain reaction: a case-control study. J Periodontol. 2007 Sep;78(9):1724-30
[5] Shah HN, Collins DM. Prevotella, a new genus to include Bacteroides melaninogenicus and related species formerly classified in the genus Bacteroides. Int J Syst Bacteriol. 1990 Apr;40(2):205-8